I imagine that we would be extinct before a lack of "pristine space" became an issue for anyone.

Ffs a black hole eats indiscriminately and we are worried about our impact on the vast nothingness we have no use for.

God forbid a piece of our trash get loose in the galaxy.

The entire earth could explode and the impact on the universe would be business as usual.

Memory transfer may never be possible. You will not experience the consciousness of the clone even if it has your memories. The clone will essentially be a separate person. It will act like you and think like you but you will still be gone.