terekkincaid

terekkincaid t1_jdn74zk wrote

Reply to comment by 3rddog in SARS-CoV-2 restructures host chromatin architecture - Nature Microbiology by Monochromaticeye

That's kind of my point. These cells wouldn't stick around long enough to be involved in long COVID. It's like saying peanut butter is found in crunchy and creamy varieties. This might help us unravel why waffles are so popular. If you're going to speculate in your discussion, you have to have some kind of hypothesis that links them logically (that leads to your next paper).

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terekkincaid t1_jdmefxd wrote

Reply to SARS-CoV-2 restructures host chromatin architecture - Nature Microbiology by Monochromaticeye

Viruses do all kinds of things to hijack a cell's machinery. The question is, how long do those cells survive? Are there SARS-CoV-2-infected cells that don't die and avoid detection by the immune system? Are they reverting to normal or semi-normal function after infection? Most cells are a lost cause after viral infection for any number of reasons. Is there a reason they expect these cells to survive and somehow cause "long COVID"? Is there a proposed mechanism?

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terekkincaid t1_ixyrl4i wrote

Reply to comment by 11061995 in TIL for the Untouchables Brian De Palma casted Bob Hoskins in case De Niro could not appear. De Palma mailed Hoskins a check for his contracted fee of $200,000 with a "Thank You" note, which prompted Hoskins to call up De Palma and ask him if there were any more films he didn't want him to be in. by KongoOtto

No, he just phoned in what I consider to be one of (if not the) shittiest performances of his career. Everyone else killed it in that movie and Di Niro acted like some Dick Tracey cartoon character. Just awful.

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