Okay cool thanks for explaining!

From what I understand, Daz is a collection of premade assets and rigs, right?

I see, to answer your previous question, a SARM will decrease your body's ability to produce testosterone on its own as well as having the deleterious effects of high androgen levels, and since it is metabolized by the liver, effect hepatic function...

An AI lowers circulating estrogen which may boost "natural" testosterone (causing the same effects from higher androgen levels) as well as the negative effects of aromatase inhibitors in general (vision and hepatic involvement). Estrogen also serves to counteract some problems caused by high androgens, so lowering estrogen in order to increase testosterone may negatively effect blood pressure, cholesterol, lipids, joint health, electrolyte balance.

Do you mean a SERM? An aromatase inhibitor will effectively lower the body's estrogen by preventing androgens from being converted to estrogen via the aromatase enzyme. A SARM binds to and activates specific androgen receptors, to mimic the positive effects of something like testosterone, without the negatives (in theory but not in practice)

That was essentially the premise behind the development of SARMs (selective androgen receptor modulators) but in trials they never quite panned out, and negative effects were still apparent (dyslipidemia, hypercholesterolemia, elevated liver enzymes, suppression of the hypothalamic-pituitary axis, etc...) So right now it doesn't seem possible in practice with available drugs.

No, androgen receptor activation seems to improve glucose metabolism through a few pathways from what I remember. B-cell activation as well as increased GLUT1 expression and well the increase in the skeletal muscle ability to store glycogen.

There are many negative effects to chronically elevated androgens, however...

> So this article was written by people who think a 50 BMI is perfectly healthy, normal, and that a 50 BMI person shouldn't be medically or socially encouraged to lose any weight whatsoever?

Is it? Can you define weight-inclusive and the weight-normative approachs to patient health as well as their outcomes with regards to weight, physical, and mental health?