I cannot sweat, therefore, I'm very susceptible to heat-related illness. When I had my first heat stroke, the doctor said I'm more sensitive to heat now and need to be more mindful of my clothing choices, outside/indoor temperatures, monitor my body temperature, and always let any future doctor know about it because some medications can also cause a sensitivity/intolerance to heat.

This article from the '90s discusses the psychological and physiological effects of heat stroke.
This PDF discusses the thermal injuries of the nervous system after heat stroke.

There's a medical documentary on YouTube, called Drug Trial Goes Terribly Wrong: Emergency at the Hospital on a channel called Real Stories.

It's about a drug trial in the UK for a possible treatment of leukemia, which had positive results in monkeys. The reactions to the drug were severe swelling (newspaper called one guy the Elephant Man), multiple organ failure, high fevers, and several fingers/toes were amputated. Lasting effect is possible fertility issues. There was a police investigation to ensure that the drug wasn't tampered with, patients weren't intentionally poisoned, correct dosages, etc.