SlayerS_BoxxY
SlayerS_BoxxY t1_j4cgpqz wrote
Reply to How are animals given specific types of cancer for the purpose of medical experimentation? by InZerSchtinker
In addition to other answers, there are also genetically modified animals that make them predisposed to certain tumors.
In the US, scientists at academic institutions who use animals are required to abide by institutional guidelines as well as local and federal laws governing the care and use of animals (mostly applying to vertebrates only).
While not all animal studies translate to humans, it is important to keep in mind that all of the major breakthroughs in cancer treatment in recent decades (checkpoint blockade, CAR-T, etc) have been discovered in and developed using animal models. They also relied on basic immunology knowledge generated primarily from animal models.
SlayerS_BoxxY t1_j5jela2 wrote
Reply to comment by Neat_Youth470 in How our microbiome is shaped by family, friends, and even neighbors. Study of the gut and mouth microbiomes of thousands of people from around the world raises the possibility that diseases linked to microbiome dysfunction, including cancer, diabetes, and obesity, could be partly transmissible. by MistWeaver80
It is transmission. most of these bugs have no habitat outside of the mammalian gut.