You hit the nail on the head. The vast majority of the country is not able to be traveled in anything resembling an efficient fashion. I live in a county where there's no medical care of any kind outside one city. There's a few grocery stores with really limited provisions kicking around, but you have to go that city to go shopping for anything else, and it's about 50 miles away. Public transportation is a pipe dream, since the odds of anyone building 50 miles of high speed railway or doing several round trip bus routes per day to service a few hundred people, who are scattered over about 60 square miles are pretty much nonexistent. And proximity aside, in the winter, travel on foot or bicycle is pretty much a non-option due to snow and temperatures.

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I think there's a huge market for simple cars, that don't have staggering amounts of unnecessary "luxury" BS packed into them that isn't even optional. The newest car I've ever had was a 2003, and I'll keep it like that as long as I can. Sure, it's cool to have an electronic paddle shifting, keyless start, traction controlled, automatically braking, car that can take voice commands and wirelessly sync to phone, but it's not worth $80,000 to me to buy it, and the cost of maintaining all that crap is huge. If somebody still made a simple vehicle with no frills, just a simple, tried and true piece of machinery, it would cost a fraction of new vehicles today, and I think there would be a ton of people who would buy it. Whether or not that'll happen, I don't know, but it's an option.

Do you mean synthetic meat as in lab grown muscle tissue, or as in the impossible burger stuff? I honestly have a hard time seeing either of those business models scaling up enough in the next ten years to make them more affordable than actual meat from an animal.