R1ckMartel
R1ckMartel t1_it85txq wrote
Reply to comment by Silpion in Engineers at Duke University have developed a novel delivery system for cancer treatment involving a radioactive implant demonstrating its potential against one of the disease’s most troublesome forms: pancreatic cancer. by chrisdh79
There are numerous targeted molecular therapies with radiopharmaceuticals that would achieve precise localization to the tumor when attached to a ligand and chelating molecule. Hardening is irrelevant.
Lutathera is a prime example.
Why they choose I-131 is bizarre to me. It has a more mixed emission spectrum (a 364 kEV gamma) that would irradiate more of the surrounding, healthy tissue than other agents like Lutetium-177 that are almost pure beta-emitters.
R1ckMartel t1_it7rs6o wrote
Reply to comment by illPMyoumycatanddog in Engineers at Duke University have developed a novel delivery system for cancer treatment involving a radioactive implant demonstrating its potential against one of the disease’s most troublesome forms: pancreatic cancer. by chrisdh79
Yeah, there is nothing novel about this.
R1ckMartel t1_it9ke3w wrote
Reply to comment by dern_the_hermit in Engineers at Duke University have developed a novel delivery system for cancer treatment involving a radioactive implant demonstrating its potential against one of the disease’s most troublesome forms: pancreatic cancer. by chrisdh79
They're called polaxamers and are not novel:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6955690/#:~:text=Poloxamers%20or%20Pluronics%C2%AE%20are,active%20properties%20to%20the%20polymers.