Pjcrafty

Pjcrafty t1_iylaili wrote

He means that he got the highest dose of vaccine, so since it looked promising in general he may be immune since he got a big vaccine dosage.

The experimental group in a vaccine study isn’t exposed to what they’re vaccinating for. That would be extremely unethical.

They compare the vaccinated population to the unvaccinated control group in the population and see if the people who got vaccinated contract the virus at a lower rate.

So, for example, you vaccinate 10k people and have a control group of 10k people who get a placebo. Over the next 5 years, 100 people in the control group get HIV but only 2 people in the vaccine group do. That implies that the vaccine works, because ideally your control and test groups are similar enough that the only thing that makes them different is having the vaccine.

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