HappyBavarian

HappyBavarian t1_iz1hcq2 wrote

Reply to comment by theRedditUser31415 in Study in fruit flies found that the most promising anti-ageing drug rapamycin prolongs the lifespan, and the development of age-related pathological changes in the gut, of female fruit flies, but not in males. Concluding that the sex is a crucial factor in the effectiveness of anti-ageing drugs by giuliomagnifico

Rapamycin was initially developed as an antibiotic. The immunosuppressant properties have been discovered afterwards. Hence it was taken off the market. It made it's come-back some time ago for OT patients. Maybe I should have formulated this clearer in order not to confuse people unfamiliar with the substance.

I know that it is used in OT recipients, because I have been prescribing during my work.

I would rather not see it as a potential anti-aging drug because of its immunosuppressant properties and possible fatal side effects due to infection in an immunocompromised state.

Thanks for your response and the links.

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HappyBavarian t1_iz0d3q4 wrote

Reply to Study in fruit flies found that the most promising anti-ageing drug rapamycin prolongs the lifespan, and the development of age-related pathological changes in the gut, of female fruit flies, but not in males. Concluding that the sex is a crucial factor in the effectiveness of anti-ageing drugs by giuliomagnifico

Rapamycin is an antibiotic, which cannot be used in humans because it is also a potent immunosuppressive.

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