What are the best alternatives to a double-blind RCT if blinding is impossible: example you cannot have a double-blind RCT to test the effectiveness of masks against covid. What is the best way to test if masks, as worn in real life, are effective? Submitted by DenebianSlimeMolds t3_11afyr0 on February 24, 2023 at 2:22 AM in askscience 13 comments 6