Comments
Nathanlee213 t1_j2cnyb0 wrote
Never tried myself but I’ve heard it’s pretty fun in small doses. The effects are somewhat similar to being drunk. And of course you can easily take too much and be passed out.
pezident66 t1_j2co6xd wrote
Poor man's escasty.
GeneralNathanJessup t1_j2cotfv wrote
The brain has nicotine receptors. https://www.sciencedirect.com/topics/medicine-and-dentistry/nicotinic-receptor#
The brain has opiate receptors. https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/opiate-receptor
The brain has cannabinoid receptors. https://www.labroots.com/trending/videos/12752/thc-binds-cannabinoid-receptors-brain
Most drugs work by mimicking the brains own chemicals.
Another interesting fact. The industrial solvent named 1,4 butanediol is converted by the human liver into GHB.
1,4 butanediol is not a federally controlled substance, and is not covered under the Federal Analog act. https://en.wikipedia.org/wiki/1,4-Butanediol
sendnewt_s t1_j2cp1ju wrote
Researchers have identified two cannabinoid receptors: CB1, predominantly present in the nervous system, connective tissues, gonads, glands, and organs; and CB2, predominantly found in the immune system and its associated structures.
Tall-Studio2669 t1_j2cpq12 wrote
Ecstasy?
pezident66 t1_j2cpsvw wrote
Yea my bad
IAmDavidGurney OP t1_j2cq00s wrote
My point was that GHB has it's own receptor that it binds too. IE the GHB receptor is designed to have endogenous GHB bind to it. The cannabinoid receptors are designed for endocannabinoids like anandamide, not THC or CBD which the body does not produce.
ILikeLenexa t1_j2cqete wrote
The dose makes the poison.
IAmDavidGurney OP t1_j2cqtt4 wrote
Yes, but I meant that the GHB receptor is there to have endogenous GHB bind to it. Nicotinic acetylcholine receptors are designed to have acetylcholine bind to them. Nicotine binds to them but the receptor isn't there for nicotine since it isn't naturally in the brain. Opiate receptors are there to have endorphins bind to them, not exogenous opioids. Cannabinoid receptors are meant for endocannabinoids like anandamide, not THC.
Yeah, these drugs bind to those receptors but the receptors are there for naturally occurring neurotransmitters, not the drug. What's interesting about GHB is that its receptor is designed for the brains GHB.
IAmDavidGurney OP t1_j2cqzgy wrote
It's sorta like alcohol but not really. It's much more euphoric and has a prosocial/empathogenic quality. It can be stimulating in lower doses and sedating in higher doses. It's basically non toxic and produces no hangover.
Taking too much is a danger since it's potent. That's why you need a syringe to measure the dose.
iamthedialectic t1_j2csjkl wrote
If you add msg to your ferment, you're gonna get ghb in the end product. You can make it with sugar, msg, yeast, and water.
You can also easily overdose and will not know how strong it ever is, so don't make it.
dondeestasbueno t1_j2curfa wrote
Give it another 45 minutes.
mrgreyeyes t1_j2cvkwx wrote
Uncle Roger: "FUIYOH!"
iamthedialectic t1_j2cwisw wrote
dis wery good recipe
kryptikmind t1_j2d32au wrote
🧑🚀
benjavari t1_j2d5je7 wrote
Also if you take two cap fulls of ghb you'll have the greatest night of sleep you've ever had. I've roofied myself several times.
Captcha_Imagination t1_j2dnzhd wrote
Receptors are often named after the drug that activates them. When Israeli Dr. Raphael Mechoulam discovered what receptors THC and CBD bind to what did it call it? Cannabinoid receptors. The whole system is the endocannabinoid system.
Don't get caught up in the naming of it. We name the key (compound) and lock (receptor) AFTER we see them interact. I thought the same as you when I first saw stuff like this.
Alliwantispcb t1_j2dukb1 wrote
Georgia home boy
lasertitsnow t1_j2eqyxl wrote
I went on a date with a narcoleptic lady and she was prescribed GHB. It's stops attacks of cataplexy for 24 hours after taking it.
pirrozhenka t1_j2fe8s9 wrote
That's why Hannibal Lecter likes to eat someone's brain
IAmDavidGurney OP t1_j2cn1ls wrote
Of course the dose in natural products is so low you would never feel the effects.
Also, not only is GHB naturally produced in the brain but it also has it's own receptor, the GHB receptor. I don't know of any other drugs that have their own receptor. There is no THC or DMT receptor. They bind to other receptors designed for neurotransmitters.