> When the price of castor oil increased in the latter portion of the 1920s, Harry Gross, president of Hub Products Corporation, sought an alternative additive for his Jamaica ginger formula. He discarded ethylene glycol and diethylene glycol as being too volatile, eventually selecting a mixture containing triorthocresyl phosphate (TOCP), a plasticizer used in lacquers and paint finishing. Gross was advised by the manufacturer of the mixture, Celluloid Corporation, that it was non-toxic.[3][6]

> TOCP was originally thought to be non-toxic; however, it was later determined to be a neurotoxin that causes axonal damage to the nerve cells in the nervous system of human beings, especially those located in the spinal cord. The resulting type of paralysis is now referred to as organophosphate-induced delayed neuropathy, or OPIDN.[7]