It actually does if you frame it within the decline of NYC and the people in it. Each character in Mad Men is flawed in someway and is a product of their environment.

Don Draper, betty and Pete Campbell etc can behave like they do because they manipulate their social status (ironic since draper is living a lie). It shows the built in lie, that the folks from Madison Ave relied on. They sold happiness...yet characters like Irene, lori shay, Paul in the Deuce tried to buy into that happiness and failed.