It depends on how you think about it. If you're only interested in MacFarlane's directly-written work, it's hard to pin down where a lot of it starts and ends for the shows he produces. The first few seasons of Family Guy, certainly, those weird TV specials where he sings a lot, and movies like Ted and A Million Ways to Die in the West.

But if you take the broader view of the things he's INFLUENCED, with his quick-cut comedy, lack of continuity, and intentionally offensive subject matter, I'd say that all of his shows broadly match his sense of humor.

It's kind of like being a fan of Star Wars. Sure, we're now getting almost nothing directly from George Lucas. But we can all admit that some of the stuff he had the most control over was the worst in the series, and that he still gets at least some credit for inspiring the best parts.