While the show makes a point not to label either character autistic, it’s clear that they’re coded in a way to present as autistic.

I believe they are both on the spectrum, but that Amy is better at recognizing social cues and is more open to participate in social customs that she doesn’t understand due to her history being an outcast.

Also, I just recently watched the series for the first time and loved it. You’re in for a fun time.