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H2AK119ub t1_ixvvblk wrote on November 26, 2022 at 7:57 PM

Reply to comment by itwasquiteawhileago in Brain cancer vaccine succeeds at prolonging survival in Phase 3 trial by Sorin61

Your latter point is probably why this trial took such a long time to accrue patients. Also, the difference between the treatment and external control in primary disease is 3 months for OS. IME - watch and wait is used for low grade disease.