Missouri is known as being number one for puppy mills and meth production. We may have been surpassed in the meth production race in recent years...but yes, there are huge issues with homeless and drugs. I work nights, and you can't go to a gas station without being harassed for money, etc. Driving down north glenstone at night, you can see the homeless issue really bad. Not a street corner exists on the busier streets without someone riding a sign.