ZoomedAndDoomed t1_ir082t9 wrote
Reply to comment by kg4jxt in The Fountain of Life: Scientists Uncover the “Chemistry Behind the Origin of Life” by Shelfrock77
You misquoted it, the original quote is "This is the first demonstration that primordial molecules, simple amino acids, spontaneously form peptides, the building blocks of life, in droplets of pure water. This is a dramatic discovery." The Miller experiment wasn't the first to discover them in droplets of pure water, miller was the first to discover that primordial molecules, simple amino acids, spontaneously form peptides.
kg4jxt t1_ir4vaxr wrote
Are you making the distinction that the process occurred experimentally in "droplets of pure water"? First of all, by any definition the water in Miller-type experiments is not pure: it contains a mixture of gases. Second, peptides could never form in pure water for the same reason; pure water does not contain the elements necessary to construct amino acids. So the "in pure water" phrase is a bit of mumbo jumbo some creative writer at scitechdaily probably threw in there, not relevant to the quote, imho. I doubt it appears in an original publication on this work.
I have read (many years ago), that although amino acids form readily enough from ammonia and methane as precursors; getting more complex molecules was ever more hit-and-miss in these types of experiments. Partly this was thought to be due to the relatively small quantities of amino acids in the apparatus from the first-stage syntheses. So some modified experiments began with added amino acids to simulate hypothesized concentration effects, and/or adding clay or other substrate that might act to catalyze formation of more complex molecules. I do not have access to journal libraries, so I can't find better than https://pubmed.ncbi.nlm.nih.gov/26508401/ (which does not mention peptide formation).
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