> The researchers found that paternal DCHP exposure for four weeks led to high insulin resistance and impaired insulin signaling in F1 offspring. The same effect, but weaker, was seen in F2 offspring. > >“We found paternal exposure to endocrine disrupting phthalates may have intergenerational and transgenerational adverse effects on the metabolic health of their offspring,” Zhou said. “To the best of our knowledge, our study is the first to demonstrate this.”

Paper: https://www.sciencedirect.com/science/article/pii/S0160412023000429