The only advice I can provide is: try as many masks /different set ups as you can.

I couldn't really handle the full face masks. I responded really well to nasal pillows. But I also found out I needed a head strap to keep my mouth from flapping open.

It was a lot of trial and error and after a year or so it's worth reassessing and seeing what's working and what isn't.

Make sure the pressure is tuned properly, that the humidity is set up for your environment, etc etc.

My sleep doc actually gave me low dose Ambien for the first couple of nights with my machine and again when I changed masks. It helped get over the sleep anxiety/hurdle of the new machine.

I can't sleep anywhere without it.

Ive been trying so much to get used to my cpap. It's been 4 years, and I still yank it off after a few hours :(