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dv_ t1_j0rcpox wrote

Reply to comment by Sputnik_Butts in Cerebrovascular insulin receptors are defective in Alzheimer’s disease by BlitzOrion

I am not negating the risk, I am negating the claim that T1D inevitably leads to IR. That's what your statements seemingly imply. I instead state that IR is entirely separate to T1D. T1D itself does not cause IR, but it also does not make you immune to it. Again, there is the informal term "double diabetes" - when one has T1D and IR.

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Sputnik_Butts t1_j0rdlzm wrote

I think if you think about this with less bias you'll see the conclusions I see. You can be T1DM and have perfect control I suppose and never gain IR. But even perfect control won't prevent you from a tiny bit of wear and tear. You might not notice till you're 70 or 80, but by then everything will be significantly harder and the damage will add up faster.

I'm just saying as a T1, unless you're cured it's inevitable that we will get Alzheimer's even from micro adjustments. The only difference is what age we get it at.

Alzheimer's develops in healthy people without diabetes, you can't assume there's no risk for a T1. It's only logical that we have an increased risk, due to even a tiny IR gain.

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dv_ t1_j0reo1x wrote

> it's inevitable that we will get Alzheimer's even from micro adjustments

Again with the inevitability... The paper does not state anything about inevitability! And I see no other sources proving that T1D inevitably causes Alzheimer's.

> Alzheimer's develops in healthy people without diabetes, you can't assume there's no risk for a T1.

It can develop. It does not inevitably develop. The amount of old T1s with Alzheimer's is not 100%.

> It's only logical that we have an increased risk, due to even a tiny IR gain.

Some degree of IR is normal. There is no such thing as zero IR. The cause for concern is the pathological IR that is one key aspect of metabolic syndrome. And T1D does not cause that IR, nor does it inevitably (!) increase the risk for it. Occasional excess dosages do not equal persistent hyperinsulinemia.

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Sputnik_Butts t1_j0rgo07 wrote

We just disagree, I still believe that T1 causes Alzheimer's because that's what the pathology of Alzheimer's suggests to me. Have a nice life.

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dv_ t1_j0rjrlk wrote

Then say that you believe this instead of stating it as if it were a proven fact next time.

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Sputnik_Butts t1_j0rjwsd wrote

You as well kid

Actually I said "I assumed" and "I'm speculating" but only you have been writing like the words of god flow through you.

Is your bloodsugar good right now?

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faen_du_sa t1_j0seqwv wrote

Yes, you assumed and speculated, then someone chimed in with their seemingly more science based assumptions and also facts! Then you just said no, I have my assumptions.

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Sputnik_Butts t1_j0sf8wo wrote

Yeah they provided more facts, but they didnt extrapolate anything to convince me otherwise from their facts.

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