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medfreak t1_j1aprpv wrote

Reply to comment by _Chicken_Hunter in COVID-19 Booster Increases Durability of Antibody Response, Research Shows by Additional-Two-7312

https://www.annallergy.org/article/S1081-1206(22)01829-4/fulltext

Results

There were 228 subjects who had samples collected between 7 and 150 days after their primary series vaccine and 117 subjects who had samples collected in the same time frame after their boost. Antibody levels from 7 to 31 days after the primary series and booster were similar, but S-RBD IgG was more durable over time after the boost, regardless of prior infection status. In addition, mRNA-1273 post-boost antibody levels exceeded BNT162b2 out to 5 months.

Conclusion

The COVID-19 mRNA vaccine boosters increase antibody durability, suggesting enhanced long-term clinical protection from SARS-CoV-2 infection compared with the 2-shot regimen.

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