I think that was the hardest jump for me. I know it works in the gut, and so it takes time to adjust. By the time you get used to the 1 that adjustment may happen. It did for me. If your blood sugars were high before, the fatigue could be the purging of the sugar. I know that I get topical yeast infections when my body is purging sugar as well. It can also be really hard on your bladder. If you can tolerate the next month well it definitely gets better. I hope that it does and you have success controlling your sugars. Diabetes sucks. These medications and technology are really helpful managing it. My grandpa used to have such trouble. I think he would go nuts for the CGMs.