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not_cinderella t1_j2b7lht wrote

Reply to comment by Sketti_n_butter in Intermittent Fasting significantly reduced systolic blood pressure (SBP), but not diastolic blood pressure (DBP). The effects are likely due to weight loss. by glawgii

So does this mean essentially if you’re not looking to lose weight, there isn’t much of a benefit to doing IF?

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celticchrys t1_j2cy912 wrote

Anecdotally, it seems to help some diabetics I know control their fasting blood glucose levels better. There is limited data on this so far, though.

https://pubmed.ncbi.nlm.nih.gov/32780629/

It is hypothesized that it may help reduce some negative aging effects, but the articles sadly seem to all be paywalled.

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not_cinderella t1_j2cyj9a wrote

I think I’ve heard that before. But is it just type II diabetes or both type I and II?

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LuckyHedgehog t1_j2d7z42 wrote

It's far from definitive, but here's an article on Diabetes.co.uk

>A study published in February [2017] reported that cyclical fasting helped to repair beta cells in mouse models of type 1 diabetes. This may be due to the fact that autophagy is often followed by a massive boost in stem cells that can replenish or replace beta cells destroyed by autoimmune processes with healthy cells

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smurficus103 t1_j2bhnyc wrote

IF might have benifits beyond weightloss and blood pressure, there's some pretty exciting preliminary rat studies

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not_cinderella t1_j2biqzz wrote

Like what though? I already mostly eat a 12-12 (even 14-10) schedule; not on purpose that’s just how I like to eat. Is there really a lot of benefit from constraining eating further ?

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LuckyHedgehog t1_j2d75qk wrote

When your body enters a fasting state it will begin a process called Autophagy, the process of cleaning up old and damaged cells in your body

This process has a number of beneficial long term effects such as lowering cancer risks, elimination of latent viruses and pathogens hiding in older cells, triggering stem cell production, etc.

Another study about this effect, though this is using longer fasting cycles the benefits still apply for IF

https://news.usc.edu/63669/fasting-triggers-stem-cell-regeneration-of-damaged-old-immune-system/

>The study has major implications for healthier aging, in which immune system decline contributes to increased susceptibility to disease as people age. By outlining how prolonged fasting cycles — periods of no food for two to four days at a time over the course of six months — kill older and damaged immune cells and generate new ones, the research also has implications for chemotherapy tolerance and for those with a wide range of immune system deficiencies, including autoimmunity disorders

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not_cinderella t1_j2e0kgr wrote

It’s hard to wrap my head around how not eating for 4 days could be healthy, but that’s probably m personal struggle with disordered eating coming in. Thanks for the info.

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LuckyHedgehog t1_j2e2bo7 wrote

Going that long is extreme and should definitely be medically supervised to make sure you're getting the correct nutrition supplements. People do go that long on a routine as well but they have to build up to it and be very careful coming out of it to avoid refeeding syndrome

In this context they're looking at the extreme specifically for treating cancer patients

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