My family member has bipolar so I am very interested in this. My prior understanding is that is is most likely to first appear in late teens, early twenties. This doesn’t appear to have been factored into the reasoning behind this article I am not a scientist so I may be missing something. If someone could shed light on this I would appreciate it. Side note about our experience to help others. Symptoms showed up at 18 but wasn’t diagnosed until 35. Went through many meds but now on cocktail of 3 that have worked for years. Now in their 60s. 2 manic episodes since diagnosis. Cause for one is a mystery. Cause for another was donation of platelets. They knew they were going manic so got to their psychiatrist who gave meds to stop it. It took awhile. None of any of these meds work immediately- they take days or weeks. They were told to take a long walk everyday because the rhythm somehow helps regulate the brain so they have been doing that for 30 years to good effect. Have never been hospitalized. They have held responsible positions in both work and community for decades. They don’t hide their diagnosis but it rarely comes up. When it does people are shocked since this person is so stable and reliable. They have had a good life so a diagnosis is not all gloom and doom. Just wanted to give you some insight from someone who has lived with it.