InTheEndEntropyWins t1_ix3kky8 wrote on November 20, 2022 at 2:15 PM

Reply to comment by DopeDetective in Study demonstrates that how effectively an individual awakens in the hours following sleep is associated four independent factors: sleep quantity/quality the night before, physical activity the day prior, a breakfast rich in carbohydrate, and a lower blood glucose response following breakfast. by the_phet

While you think you are bad, I suspect that many people are way worse when it comes to messing up their circadian rhythm.

[deleted] t1_ix3l3k4 wrote on November 20, 2022 at 2:20 PM

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DopeDetective t1_ix3lc4t wrote on November 20, 2022 at 2:22 PM

well sure but they're saying there's no genetic component yet we know that sleep is strongly influenced by genetics & so is liver function such as diabetes and glucose response

InTheEndEntropyWins t1_ix3nueq wrote on November 20, 2022 at 2:42 PM

> we know that sleep is strongly influenced by genetics

I'd argue that very little is genetic compared to environmental factors.

This study used identical twins, so they were able to control for the genetic factor and measure the impact of environment.

So, while they say there was no genetic component, I think was it means is the genetic component has no material impact compared to environment.

DopeDetective t1_ix3ogzc wrote on November 20, 2022 at 2:47 PM

well for example, a person could eat well, exercise daily, and go to bed with time for 8hrs of sleep but if they have sleep apnea or insomnia (genetic conditions) theyre still not going to wakeup feeling rested.

on the other hand, there are people with a gene that allows them to only need 4hrs of sleep so they would be just fine staying up super late

people with diabetes (genetic) can't have high carb breakfasts and their glucose response doesn't work so they will never achieve all 4 of these important things & that's caused by genetics

InTheEndEntropyWins t1_ix3sog9 wrote on November 20, 2022 at 3:19 PM

>well for example, a person could eat well, exercise daily, and go to bed with time for 8hrs of sleep but if they have sleep apnea or insomnia (genetic conditions) theyre still not going to wakeup feeling rested.

OK I agree there may be some people with genetic diseases, but I think they would be in the minority. I would also class type 2 diabetes and apnoea as primarily environmental issues, due to them being overweight/obese rather than purely being a genetics issue.

I think for most people the above is impossible. In that for the vast majority of people if they have a regular routine, exercise, get the right amount of light at the right time, etc. then they won't have insomnia.

DopeDetective t1_ix41g8p wrote on November 20, 2022 at 4:22 PM

what about type 1 diabetes? type 2 diabetes is also genetic

i guess my issue is that they really only looked at healthy people. if you exclude a bunch of people who have a genetic predisposition then of course youre not going to find a genetic relationship

"Study participants were healthy individuals aged 18–65 years, who were able to provide written informed consent. Exclusion criteria included ongoing inflammatory disease; cancer in the last three years (excluding skin cancer); long-term gastrointestinal disorders including irritable bowel disease or Celiac disease (gluten allergy), but not including irritable bowel syndrome; taking immunosuppressants or antibiotics as daily medication within the last three months; capillary glucose level of >12 mmol l–1 (or 216 mg dl–1), or type 1 diabetes mellitus, or taking medication for type 2 diabetes mellitus; currently experiencing acute clinically diagnosed depression; heart attack (myocardial infarction) or stroke in the last 6 months; pregnancy; and vegan or experiencing an eating disorder or unwilling to consume foods that are part of the study. "