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phdoofus t1_iwt4j8h wrote

Reply to comment by ConqueredCorn in Study finds age-related macular degeneration strongly associated with serious forms of cardiovascular disease, heart damage from heart failure and heart attacks by Living_And_Alive

Maybe but by the time he came down with MD we were all surprised he hadn't already had a heart attack

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Last-Initial3927 t1_iwt6xpu wrote

Had heard a little about this before under the “lipotoxicity” hypothesis of MD where extracellular fat exerts stress on retinal cells and is “organised” by secreted lipoproteins. I believe it was a cycle of disrupted cell architecture (diminishing surface area) and increased local metabolic derangement.

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