Welcome to r/science! This is a heavily moderated subreddit in order to keep the discussion on science. However, we recognize that many people want to discuss how they feel the research relates to their own personal lives, so to give people a space to do that, personal anecdotes are allowed as responses to this comment. Any anecdotal comments elsewhere in the discussion will be removed and our normal comment rules apply to all other comments.

I am a bot, and this action was performed automatically. Please contact the moderators of this subreddit if you have any questions or concerns.

Great. Add it to Semeglutide (of course there are better ways, I'm not saying add it to the water, some people need the help though) , drop the cost to something affordable and then watch the cost of healthcare plummet?

Depends where you are. Here in the US cost stays the same, it's just the profit that skyrockets.

Well, that's what I mean. I am in the US and something needs to change.

Until healthcare in the US isn't just another business I doubt it'll ever change

[removed]

[removed]

[removed]

Apparently, fear of needles contributes greatly to anti-vaxx feeling.

The real reason many people don't vaccinate is because they're scared of the needle. As they know this is a childish reason, they then accept anti-vaxx conspiracies as a way to justify it to themselves.

[removed]

Ah yes, as we know, science is only capable of focusing on one thing at a time.

Now that's a conspiracy theory

Perhaps useful for long acting insulins, but I assume the delay in entering and being absorbed in the GI tract would make this pretty infeasible for short acting insulins, which comprise the majority of shots for type 1 diabetics at least.

No, there has been actual research on this. Found it on this sub.

Can't find the paper right now unfortunately, but I have found some other related articles: https://theconversation.com/over-half-of-adults-unvaccinated-for-covid-19-fear-needles-heres-whats-proven-to-help-161636

https://www.bbc.co.uk/news/newsbeat-58086377

1 in 10 people fear needles, and half of those that haven't vaccinated do so. That is a massive correlation. This technique could be massively beneficial: at best it could reduce unvaccinated population by half.

Meanwhile I have RA and prefer taking meds with needles (once every two weeks) instead of having to take a pill daily.

Which is crazy since high gauge needles are essentially painless. It’s the preservatives in the vaccine itself which are painful.

They have. It’s called Rybelsus. It requires more of the active drug per dose than the injectable to survive the digestive tract.

I take a once weekly injection, would love to replace it with a pill instead.

Diabetics do not have a fear of needles... if they do they got over them really quick...

The speed at which whatever volume of solution also can contribute to pain at the injection site. Faster injection of more solution hurts more

But Americans won’t be able to afford any of it

[removed]

[deleted]

I dont know about you but think about it this way instead of being so negative.

If I was a severe Type 1 diabetic I could be having to wear a constant blood monitor and give my self shots with every meal.

Then someone came along and just said here take this pill once a day.

Does that really not sound like an improvement to you?

I'm hoping this research becomes cheap and affordable, though it wouldn't surprise me if some of the bigger pharma companies buy it out somehow and burry it.

Not at all. There is still plenty of research into complete cures.

But in the meantime there is also opportunities to improve quality of life.

That is why clinical trials are conducted. New drugs don't make it to the market if they are dangerous.

Anything that allows needles to be avoided is a good thing. I spent 2 years in dialysis and the needles were so painful.

I'm a type 1 diabetic with multiple tattoos and definitely not anti vax... I'm still afraid of needles

Oral meds are often effective within 30 min. Is that not fast enough?

I don't think the point of this comment was specific to diabetic patients, and more about lifting barriers to vaccination, improving vaccination rates

[removed]

Right, for a type 1 diabetic it's difficult to see how this would work. If you use an insulin pump, it provides a basal rate of insulin delivery as well as bonuses, as needed. Would the idea be to take an oral long-acting insulin as well as pills of short-acting insulin as needed? At some point, this becomes a lot of pills.

Not sure how quickly it would be absorbed. But even rapid acting insulins like Novorapid take 2-3 hours to take full effect.

Nationalize it!

That’s not really a good way to describe it. They start taking effect much sooner and their action is usually finished by ~3 hours. For stopping blood sugar spikes, the faster it begins working the better.

Of course dude, like what do you think, that there are multiple scientific institutions? What?!?

Who exactly do you imagine "they" is?

I'm not specifically talking about diabetes patients.

Literally taking what I said from a commercial on tv for a drug that is already on the market. And I have heard on many occasions that deaths have a occurred from complications after taking a particular drug.

Every drug commercial you see has side effects that seem like trading one thing for another. Granted the bad effects only apply to probably 2% of users, but still.