Submitted by giuliomagnifico t3_ytdnui in science
Depends where you are. Here in the US cost stays the same, it's just the profit that skyrockets.
Well, that's what I mean. I am in the US and something needs to change.
Until healthcare in the US isn't just another business I doubt it'll ever change
Nationalize it!
They have. It’s called Rybelsus. It requires more of the active drug per dose than the injectable to survive the digestive tract.
Perhaps useful for long acting insulins, but I assume the delay in entering and being absorbed in the GI tract would make this pretty infeasible for short acting insulins, which comprise the majority of shots for type 1 diabetics at least.
Oral meds are often effective within 30 min. Is that not fast enough?
Not sure how quickly it would be absorbed. But even rapid acting insulins like Novorapid take 2-3 hours to take full effect.
That’s not really a good way to describe it. They start taking effect much sooner and their action is usually finished by ~3 hours. For stopping blood sugar spikes, the faster it begins working the better.
Right, for a type 1 diabetic it's difficult to see how this would work. If you use an insulin pump, it provides a basal rate of insulin delivery as well as bonuses, as needed. Would the idea be to take an oral long-acting insulin as well as pills of short-acting insulin as needed? At some point, this becomes a lot of pills.
Meanwhile I have RA and prefer taking meds with needles (once every two weeks) instead of having to take a pill daily.
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I take a once weekly injection, would love to replace it with a pill instead.
Anything that allows needles to be avoided is a good thing. I spent 2 years in dialysis and the needles were so painful.
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But Americans won’t be able to afford any of it
I'm hoping this research becomes cheap and affordable, though it wouldn't surprise me if some of the bigger pharma companies buy it out somehow and burry it.
Apparently, fear of needles contributes greatly to anti-vaxx feeling.
The real reason many people don't vaccinate is because they're scared of the needle. As they know this is a childish reason, they then accept anti-vaxx conspiracies as a way to justify it to themselves.
Now that's a conspiracy theory
No, there has been actual research on this. Found it on this sub.
Can't find the paper right now unfortunately, but I have found some other related articles: https://theconversation.com/over-half-of-adults-unvaccinated-for-covid-19-fear-needles-heres-whats-proven-to-help-161636
https://www.bbc.co.uk/news/newsbeat-58086377
1 in 10 people fear needles, and half of those that haven't vaccinated do so. That is a massive correlation. This technique could be massively beneficial: at best it could reduce unvaccinated population by half.
Which is crazy since high gauge needles are essentially painless. It’s the preservatives in the vaccine itself which are painful.
The speed at which whatever volume of solution also can contribute to pain at the injection site. Faster injection of more solution hurts more
Diabetics do not have a fear of needles... if they do they got over them really quick...
I don't think the point of this comment was specific to diabetic patients, and more about lifting barriers to vaccination, improving vaccination rates
I'm a type 1 diabetic with multiple tattoos and definitely not anti vax... I'm still afraid of needles
I'm not specifically talking about diabetes patients.
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That is why clinical trials are conducted. New drugs don't make it to the market if they are dangerous.
Literally taking what I said from a commercial on tv for a drug that is already on the market. And I have heard on many occasions that deaths have a occurred from complications after taking a particular drug.
Every drug commercial you see has side effects that seem like trading one thing for another. Granted the bad effects only apply to probably 2% of users, but still.
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Ah yes, as we know, science is only capable of focusing on one thing at a time.
Of course dude, like what do you think, that there are multiple scientific institutions? What?!?
I dont know about you but think about it this way instead of being so negative.
If I was a severe Type 1 diabetic I could be having to wear a constant blood monitor and give my self shots with every meal.
Then someone came along and just said here take this pill once a day.
Does that really not sound like an improvement to you?
Not at all. There is still plenty of research into complete cures.
But in the meantime there is also opportunities to improve quality of life.
Who exactly do you imagine "they" is?
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cosmoboy t1_iw3luyf wrote
Great. Add it to Semeglutide (of course there are better ways, I'm not saying add it to the water, some people need the help though) , drop the cost to something affordable and then watch the cost of healthcare plummet?