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kvotebloodless t1_ivboddv wrote

Reply to comment by arkteris13 in Metabolic and physical function are improved with lifelong 15% calorie restriction in aging male mice (Nov 2022) by basmwklz

In the biology of aging course we talked about this too. You could assume by giving mice access to food 24h a day, they will eventually just be over fed. And by limiting the diet to a healthy amount, their life will be naturally elongated. So the calory restriction theory is not as proven as many say.

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triffid_boy t1_ivceurb wrote

These aren't the only studies that suggest a benefit to CR, and the mechanism - via mTOR - is reasonable.

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Elphya t1_ivdokya wrote

"You could assume by giving mice access to food 24h a day, they will eventually just be over fed."

Anyone that works with mice in animal facilities knows that's not true.

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