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oldastheriver t1_iutrn5z wrote

Reply to comment by TheManInTheShack in Single-Dose Psilocybin for a Treatment-Resistant Episode of Major Depression | NEJM by 9mac

oh really? I am active in the sub Reddit for psilocybin, and these side effects are very common. And it's also very common for people that are already diagnosed with major problem depression to experience suicidal ideation, because in order to get the diagnosis that's one of the necessary symptoms. So that aspect of it is a bit disingenuous but the headaches nausea etc. is the common reaction to a healthy dose

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SpaceObama t1_iuu0bru wrote

I wish this study differentiated between suicidal ideation and suicidal behaviours during the trip.

From my own experience, mindset and physical setting are hugely influential to a trip. I wonder what the setting was like. Alone in a university hospital clinic on psychedelics sounds horrifying. Alone in general is a bit intense. Ideally you need a good trusted friend, but I don’t know how to replicate that in a clinical setting.

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oldastheriver t1_iuu255j wrote

I had an interesting conversation with someone who was sexually molested by their father at the age of seven, basically they have suicidal ideation every day, and they are on prescription medication, the the best most effective whatever works. Yeah it's a big problem in this study. It's what I call jumping to conclusions

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SaltZookeepergame691 t1_iuvrynt wrote

Rates of suicidal ideation were low and similar between all groups. The only events of “severe” suicidal ideation were balanced across groups and happened after day 1. Data is in table 3.

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PickledPixels t1_iuv16by wrote

Anecdotally, I've eaten mushrooms dozens of times and I don't think I've ever had a suicidal ideation. I don't know what kind of atmosphere you would have to be in for that..

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oldastheriver t1_iuyielw wrote

I mean I would like to think that people that are suicidal every day, hence they have major depressive disorder, I would like to think that you know eating a mushroom would give them one day without those feelings. But it's more likely that it just opens a window, it may not even be an entire day, without depression.

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TwoHundredPlants t1_iuvym9v wrote

I haven't read this exact paper, but most psychedelic researchers have created a standard treatment protocol, usually two other adults in the room (a therapist/guide and/or researcher), and a calm environment (couches, blankets, low light, soothing music, headphones, plants, etc). I've read zero current research where someone is left alone or is in a standard bright clinic space.

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TheManInTheShack t1_iutrva2 wrote

Interesting. I’ve just never heard of side effects like that. Whenever it’s being discussed no one ever mentioned side effects (other than the possibility of having a bad trip).

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oldastheriver t1_iuu2j25 wrote

I think everybody's being pressured into accepting a scenario that's not real. I tried the psilocybin and was surprised at how sick I got, and it wasn't sickness before I was tripping but it was sickness during the trip. The sickness was coming on slow and the tripping was coming on fast and it was very unpleasant. And when I reported back to the group, everybody said yeah that's how it is. these symptoms are under reported, by the people that are extremely zealous and getting grant money.

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paranoidwerewolf t1_iuucx7w wrote

Also, saying that you tried “the psilocybin” makes you sound like a Narc.

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oldastheriver t1_iuuv3zb wrote

okay? Whats yur point?

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mauinion t1_iuxdrz0 wrote

Snitches get stitches

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oldastheriver t1_iuxxhi5 wrote

"It's just my little way of sticking it to the man" ... "but Sir, you are the man!" ... "well then It's just my little way of sticking it to myself"

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TheUsher t1_iuwd7ff wrote

For this reason, I am not trying shrooms, and I'm going with LSD instead. I don't need shroom side effects like gastro distress (got enough) or racing heart issues I saw as common. A friend told me LSD is much better and easier on your body. I'm sold.

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