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ALEX7DX t1_isss93o wrote

Is there anything it can’t do?

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Dawrin t1_istn92o wrote

It is incredible just how many secondary conditions it brings out. I’ve been following the uptick in autoimmune diabetes (t1) as the pandemic wears on, I am among the people who were diagnosed in that timeframe so this is partially a selfish interest.

But again I’m struck by just how many things get brought on, I get that it is an incredibly challenging disease for the body to handle and it seems to get into so many systems from the brain to the endocrine. We will be seeing new articles about these things and long covid for a long time it seems

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ashkestar t1_isu133n wrote

To be fair, autoimmune diseases have upticks after pretty much any widespread viral illness. It’s something we’ve known about, but now we’re seeing it on a new scale because so many people have been infected with this one.

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CornishCucumber t1_isv2dw3 wrote

I had Graves disease - a thyroid autoimmune disease almost immediately after the pandemic hit. Perfectly healthy, no history of it in my family, then boom - 3 years of my life effectively ruined. I don't think it's a coincidence at all.

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jpk073 t1_it3iusi wrote

I have Graves too but I got it pre-pandemic. Was perfectly healthy and boom here we go. I think I had a weird virus first, flu-like symptoms but not the flu.

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CornishCucumber t1_it3k9yx wrote

Now you mention it... Exactly the same as me. In the UK - had some kind of flu about 2 months before the pandemic. I had flu like symptoms around the Christmas time (November I think). Diagnosed with Graves 2 months later.

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MovingClocks t1_isu314x wrote

It helps that this is a superantigen that bears similarity to more than a few proteins in the body.

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VoilaVoilaWashington t1_isuu7qy wrote

I'm curious about how much of this will be unique to COVID-19. A friend of mine has long covid, with substantially reduced energy and all that, which was severe for over 6 months after he got out of the hospital... on oxygen for 4 weeks.

Any severe infection or injury is going to have various long-term effects, and we already know that many viruses can cause a lot of these knock on effects.

This isn't to minimize the effects of covid, but rather to advise that we shouldn't be dismissing the next pandemic just because it's not killing people in the short term. Balancing short term pain for society against millions of people with lifelong effects from the disease is difficult, but there has to be one.

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3kixintehead t1_isuq93h wrote

Its because its such a generalist disease. Most people have been referring to it as just another respiratory disease for most of the pandemic, but its entry receptor is all over the body in particular vascular cells and epithelial cells. Anything that affects the vascular system has the potential to affect everything.

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Nurokatt t1_isukexs wrote

Considering all the various organs and systems it can affect, I'm curious to see its relationship and effects on the fascial system, which pervades the entire body down the cellular level.

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happysheeple3 t1_isu474m wrote

I hope we get one that explores a possible risk stratification for serious outcomes from covid-19 with varying intakes of added sugars (sucrose, fructose and high fructose corn syrup)

The average American consumes around 57 pounds of sweeteners per year. Added sugars including sucralose and aspartame have been found to be Pro-inflammatory and could very well take a large part of the blame for the covid-19 "cytokine storms" described in the literature.

>Fructose pathway involved in oxidative stress and inflammation. In the hepatocyte, fructose sugar is rapidly metabolized by KHK, depleting ATP and resulting in uric acid accumulation. Uric acid activates NADPH oxidase with production of ROS, which activates mitochondrial ROS production and stimulates UPR in ER. ER stress may also activate mitochondrial ROS production and vice versa. Moreover, ER stress contributes to progression of hepatic steatosis activating lipogenic genes via PERK, ATF4, and IRE1 and inducing SREBP-1c that increases the activity of ACC and FAS. As a response of excessive oxidative stress, inflammatory and apoptotic pathways are activated through JNK, NFkB, and CHOP, resulting in an increased production of cytokines (IL1ß, TNFa, IL19), which plays an important role in the development of NASH.

https://www.mdpi.com/2072-6643/13/4/1314/pdf

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greyrobot6 t1_isukecm wrote

Recently started acupuncture for tendinitis in my arm that has been extremely resistant to treatment for ongoing 3 months now. Can’t get past the pain. Dr put me on a keto diet for 2 wks to jumpstart decreasing the inflammation in all of my body due to sugar. The only time I actively put sugar in anything was the 2 tsp in my morning coffee, then water all day. I don’t even have a sweet tooth. But everything else I’ve been consuming has so much added sugar! Products that are labeled light have more added sugar than full fat products. There is so much more, it’s been eye opening and I’m already feeling a difference. This has made me getting Covid as I am right now an even bigger fear.

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aelis68 t1_isv1mqk wrote

Interesting. I had issues with my arm pre-CoVID that disappeared after a few months of Vitamin D 10k iu/daily after testing showed I had almost none. I’m convinced that helped me stay CoVID free until finally coming down with it last month.

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happysheeple3 t1_isus0ew wrote

I'm so happy to hear a Dr. that's willing to say that! So many of them mindlessly believe what they're taught in school which in many cases is antiquated or outright false information. It warms my heart to hear that!

If you don't partake in marijuana already, try a THC tincture. Make sure it's full spectrum and isn't flavored. I had inflammation which I saw great improvement in when I started. CBD can work too, but it isn't as strong and the effects don't last as long, at least in my personal experience.

If you're easily addicted to things, stick with cbd.

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greyrobot6 t1_isutyb0 wrote

Indica every night for sleep. It does help with the pain until I fall asleep as well but the straight CBD tincture hasn’t worked as well for me and being stoned all day isn’t an option for me. I didn’t notice any obvious improvement with the inflammation anyway. The herbs the Dr has me on taste pretty horrendous but have helped considerably already.

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happysheeple3 t1_isvq1ib wrote

I take it before bed and I don't ever feel high. It only takes 25mL of the full spectrum tincture to get results. Music will sound a little nicer, but no head rush unless I overdo it with like 75mL.

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Pinktuxcat t1_isvjfza wrote

I have a coworker who developed diabetes from covid as well, it's not being managed well mostly because her doctor is a moron and she hangs on his every word. She does not need to use insulin as far as I know. Is there any specific treatment you've been doing? Any advice I could pass on?

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Dawrin t1_isw3zu1 wrote

I think that most people could appreciate the care and effort from somebody else wishing the best for them, but I personally (and many of the folks from /r/diabetes_t1) wouldn’t appreciate somebody suggesting how they should improve on managing their new disease. Everyone goes through the adjustment process differently and that honestly could be more of a setback.

But I will say I was misdiagnosed as t2 for several months until I visited with an endocrinologist who ordered the right tests to differentiate between the two (c Peptide to determine insulin production and an antibody test to determine autoimmunity).

Now I don’t know what your relationship with your coworker is, but I wouldn’t say anything unless they asked for any input. I understand the frustration of seeing somebody not doing well in managing their issues but this is really a “they need to help themselves before you can help them”.

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Strazdas1 t1_isx3lpf wrote

The receptors it attacks are present in many parts of the body so the lasting effects will undoubtedly also be varied.

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Minimum-Passenger-29 t1_isukg9i wrote

Incredible is the word alright. Nothing that has been said about this virus has been credible, not a damn thing.

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Zachbnonymous t1_isu05f2 wrote

Makes me wonder if other ailments don't have these risks too, but they just haven't been researched as much

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bigthingstuff t1_iswp47w wrote

Most other ailments don’t attack the entire body the way COVID does.

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GrokFu t1_isvno6m wrote

It can’t go away apparently

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WhatIfIToldUu t1_isvjqz4 wrote

Inhibit actual scientific data for the garbage shots.

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