Wagamaga OP t1_itfybe4 wrote
Stem cell-derived neurons from combat veterans with and without post-traumatic stress disorder (PTSD) provide insights into how genetics can make someone more susceptible to developing PTSD following trauma exposure, according to a study conducted by scientists from several research institutions, including Yale School of Medicine.
Post-traumatic stress disorder can develop following severe trauma and is an enormous public health problem for both veterans and civilians. However, the extent to which genetic and environmental factors contribute to individual clinical outcomes remains unknown.
To bridge this information gap, the research team studied a cohort of 39 combat veterans with and without PTSD who were recruited from the James J. Peters Bronx Veterans Affairs Hospital. Veterans underwent skin biopsies and their skin cells were reprogrammed into induced pluripotent stem cells.
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