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SaltZookeepergame691 t1_jda16in wrote

It’s a single arm phase 1 study with a handful of patients. It is fundamentally impossible (and irresponsible) to claim that this drug “extends… patients’ lives” on the basis of an uncontrolled study. There is a huge way to go before efficacy can be claimed.

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Bird_skull667 t1_jde8iq4 wrote

Right? I am also extremely wary of any article that uses the term 'cancer' with no qualifier. Which cancer? Which subtype? Breast cancer alone has like 4 subtypes with different genetic mutations driving those as well. Pancreatic cancer is not lung cancer is not leukemia. 'Cancer' is broad a term its almost meaningless except to describe something as apposed to another totally different disease type.

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vivaldop t1_jdgpymt wrote

Not a doctor so those are just my supposition using my medicao knowledge.

terminal stage cancer are extremely similar in the way that the metastasis all around the body makes the treatment impossible and therefore, the cancer type doesn't matter anymore since everything is affected.

Edit : this was false, i'm glad i kept myself aware to be proven wrong.

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Bird_skull667 t1_jdgu95l wrote

This is false. Metastatic Colon cancer in your brain is colon cancer, not brain cancer. Breast cancer in your liver is breast cancer, and both are treated based on the type of cancer you have. Cancer treatments, even for metastatic disease are based on the mutations and drivers of specific cancers. It's why there are different types of chemo, immune therapies, CDK inhibitors, surgeries, etc. 'Cancer' describes a wide range of different genetic mutations that cause malignant growth of cells, but it is not one thing. This is also why there is no one cure, or treatment, for all cancers.

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veltcardio2 t1_jdeiyq8 wrote

This is the correct comment. Needs more research and even more trials before efficacy trials. Too early

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