My dad had Bladder cancer a bit more than a decade ago. I think he was around 58 at the time he found out. He'd been a daily smoker of cigarettes for most of his life (had quit around 5 years prior) but also a daily toker. His doctors told him he was fine to keep smoking, and actually encouraged it for several reasons (appetite being the main one). Thankfully it never got out of hand, and weirdly they used localized TB to treat it.