I've been collecting microbiome-related studies as of late. The body itself - not just the brain or the mind - absolutely alters or even creates certain psychological states. Anecdotally, I've found that taking a couple of grams of GABA on an empty stomach is a way to evoke the way "body anxiety" feels, likely because the body overzealously pushes out the excess GABA , leaving a momentary shortage (localized to the neuron clusters in the gut because dietary GABA cannot readily pass the blood-brain barrier). The sensation is distinct and can be recognized, helping one overcome it by compartmentalizing it once it's identified.

Here's a relevant study relating to IBS specifically posted here a couple of days ago:

>New research establishes a link between irritable bowel syndrome and mental health challenges, such as anxiety, depression, and suicidal ideation --

>https://link.springer.com/article/10.1007/s11845-022-03258-6

And semi-related:

>Regular use of laxatives is associated with more than a 50% increased risk of developing dementia --

>https://www.aan.com/PressRoom/Home/PressRelease/5048

Pinging /u/Ok-Cut4890 too.