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CrateDane t1_j96s3pv wrote

Reply to comment by KetosisMD in Pharmacological vitamin C inhibits mTOR signaling and tumor growth by degrading Rictor and inducing HMOX1 expression (Feb 2023) by basmwklz

Well, Rapamycin mainly inhibits mTORC1, while this seems to target RICTOR for degradation and thus preventing assembly of mTORC2. So they would have complementary roles if you wanted inhibition of both complexes.

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