Pro-Karyote t1_j7wp06j wrote
Reply to comment by tjeulink in According to a study on 12,211 patients, aspirin is just as effective at preventing blood clots as low molecular weight heparin, but it costs less and is easier to administer by giuliomagnifico
It has to do with a unit of measurement we don’t currently use for dosing medications, called a grain. The full dose of aspirin was 5 grains, which is about 325mg. The low dose was a quarter of the full dose, so 1.25 grains (which is roughly 81mg). That was the dose that was on formulary, and since it falls within the low-dose range and it was the dose available, it stuck.
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