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ApprehensiveTry5660 t1_irfn8fv wrote

Reply to comment by TheTrueLordHumungous in “Scientific progress is thwarted by the ownership of knowledge.” How Karl Popper’s philosophy of science can overcome clinical corruption. by IAI_Admin

By your standards, are pride bars not pride bars if hetero individuals (who represent a much larger portion of the population already) frequent them at a high enough rate to be the majority?

A system can be defined just as much by a featured minority. A system that allows even 1/100 drugs to make it through erroneously because you bribed the right combination of senators and researchers seems rather fair to label rigged. Sure, there’s a functioning system along side of it, but there exists a mechanism for avoiding its rigors and it has been exploited rather openly and documented in court cases with opioids most famously.

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TheTrueLordHumungous t1_irgg8ed wrote

> there exists a mechanism for avoiding its rigors and it has been exploited rather openly and documented in court cases with opioids most famously

How were the clinical trials for opioid pain killers exploited? Are opioid pain killers not effective for reducing pain?

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ApprehensiveTry5660 t1_irhsg56 wrote

They obfuscated the risk of addiction throughout the 90’s. Medical literature describes the tolerance to addiction cycle in these drugs as early as the 50’s, it isn’t like it was unknown. When faced with the sharp rise in Opioid deaths post 2000 they convened a panel of experts in 2002, early enough to reign in the off label prescriptions, the panel of 10 experts they brought in had 8 members with significant financial ties to Purdue Pharmaceutical. It wouldn’t be until 2013 before any serious steps were taken, at which point there were enough pills on the market to give every adult in the United States a full bottle.

They were able to prescribe off-label, over produce, and flood both forward facing and black markets for over a decade before any meaningful action was taken. Yes, they absolutely work. They were just way more addictive than the FDA was willing to regulate, and often even recognize.

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