It’s possible but it’s really optimistic.

Coming from uptown you have to transfer to the R to Queens Plaza to get to the E. So you’re waiting for your downtown train, your transfer to the E, and then the E. When the trains are running its nice but delays are going to fuck you. Plus the E is admittedly very nice when its running express but at night when its local its a slog. You gotta wait like 20 minutes for a train and then you’re looking at an hour from that point to get to Penn Station. And then there’s been the problem w Jamaica station being shut down on the weekends/at night so you need to take a shuttle bus. There’s just a lot of variables that can drastically effect the time. So it can be 30 minutes and during peak times on weekdays it runs well enough (still not enough trains though lol) but speaking as someone who makes a daily commute from the Bronx to Jamaica the subway just really sucks getting you there consistently.