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CatumEntanglement t1_iydc63w wrote

But there is no breakthrough. This drug, like Aduhelm which is already out, does not slow not stop Alzheimer's disease. All people who get the treatment still progress in the same degree as withoit treatment. This drug is the same kind of treatment that Aduhelm is, which is a monoclonal antibody for plaques. Your statement that there are 0 drugs targeting amyloid is incorrect, as Aduhelm is already out for the public.

95% of all AD cases are sporadic with no genetic cause, the other 5% are from familial AD. These antibody drugs fail to do anything for sporadic cases and the only people there is any difference is with the 5% familial group. And that treatment difference disappears after a few months with the disease progress continues. The drug causes brain bleeds in more people than it does treating Alzheimer's.

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