Bit of a matter of taste there. He built his brand essentially in one kind of mode and set a certain standard. The films that make up what could be described as "Cronenbergian" are essential.

But he did shift gears and I find his 2000s films are quite excellent, though give or take eXistenZ he had moved away from the goop quite a bit for most of the 90s already.

Crimes of the Future is very interesting as it exists now, made so late in life but it's even more interesting when you consider it was actually written and almost got made right about the time of eXistenZ.

Crimes of the Future really feels like Cronenberg looking back at what he had done at that point. Artists telling stories about artists always brings some assumption of self commentary or insert and in the case of Saul Tenser, there is some self criticism. Through Saul Tenser, the artist making an art of cutting out his New Flesh, and actually being cop suppressing others, the film reflects that Cronenberg's approach to 'body horror' and changing technologies was more than a bit reactionary. As much as it defined his brand, that kind of transformation and change, and the real life anxieties they reflected were a source of horror. In Crimes of the Future, Cronenberg imagines an oncoming generation that truly embraces those changes and celebrates the beauty in it. Saul Tenser is a bit self conscious when others say they're following his example as he recognizes that they are at root really doing something different and moving beyond him. Locating that writing and self reflection at the end of the 90s and right before he started that run of films with Mortenson that followed it really does seem like he was consciously not just setting his earlier work aside but coming to terms with it before moving on. Fascinating to finally see it made 20 years later with a whole other phase of his career between.

So no, I don't think Cronenberg peaked creatively in the later career, but I do think he gained some perspective. Also, not sure the younger Cronenberg ever made anything quite as funny as Crimes.