That extra bit of resolution can be a double-edged sword, but it's mostly good. Depending on what you listen to, it might make you aware of how poorly produced/recorded some of your music is, but it will also let you experience how wonderfully a lot of other music is produced/recorded.

FWIW, I primarily listen to Spotify. I can hear the difference doing A-B comparisons to something like Apple Lossless, but I pretty much have to be doing back-to-back listens. You'll hear more difference between a well versus poorly produced track than you will Spotify versus something else.