You ever played Don't Starve? The single player iteration really gives off this feeling of isolation. Oftentimes, when it's dark outside and you don't really have a lot of resources to waste running around, you find yourself just watching the fire, listening to it crackle as an insect or a bird sounds off somewhere in the distance.

In the daytime, you can run and run all day long and it's just mile after mile of lonely wilderness.

It's an oddly relaxing game for me.