Prinzka t1_jefa5l9 wrote
Reply to comment by psychrolute in ELI5: If benzodiazepines are CNS depressants, why is it so hard to die from a overdose of them alone? by psychrolute
>9.5 grams of Diazepam
That's like 1 full gram of lorazepam.
I had a 1/20th of that and I only remember a few seconds of that day (and felt the after effects for multiple days).
How do you even get that much? That's like a soda bottle full.
RLDSXD t1_jefx36r wrote
Anyone not familiar with them would be absolutely shocked how cheap and available RC benzos are. I love them and even I think it’s pretty scary.
Ericrobertson1978 t1_jeg7elp wrote
I had to stop taking benzodiazapines altogether after getting C-LAM. That shit is bad decision making incarnate.
I would always start with the very best intentions, but then it would kick in and I'd inevitably black out and wake up in jail or the hospital a few days later.
I wish I could take benzodiazapines to sleep, but instead of going down, I wanna go on some idiotic adventure. I become a mindless automaton and shell of my former self.
Now I don't use them at all, if only to avoid prison and death.
They are certainly terrifying. Lol
epanek t1_jegciew wrote
I saw my PCP for anxiety during presentations. I was set to give a full day presentation to about 100 people I didn’t know. I was doing it only because our vp of marketing liked my look and presentation ability. Needless to say my two year hiatus from the subject did not help.
My dr gave me klonopin. Only take if anxious. Lol. Well those things worked too well. 6 months later I was eating them like candy. Serious problems and memory impairment. I remember visiting a customer in a complicated office park with my boss. I literally could not remember each morning how to get there. It was bad. I knew I had a problem.
The detox is deadly like alcohol.
shockencock t1_jegefyy wrote
Funny they didn’t give you propranolol for stage fright. Not a benzo either
epanek t1_jegi9jc wrote
I take propranolol now. No physical anxiety and mental sharpness
metamongoose t1_jegv15t wrote
I read PCP as the dissociative drug not a doctor, really throws your comment for a loop!
epanek t1_jeh2cow wrote
Oh damn. 😂
123rune20 t1_jeg957x wrote
CLAM is like the craziest of them all I swear. Forced myself to never look into it again.
Simple_Bass_5564 t1_jegbgkz wrote
CLAM?
nocolon t1_jegck4f wrote
Per Google it’s Clonazolam, some kind of super benzo.
RLDSXD t1_jegticv wrote
Third most potent benzo I’m aware of. Flunitrazolam and flubromazolam seem to be a bit more potent, but clonazolam was much more popular because flunitrazolam only lasts like two hours and flubromazolam was way too hypnotic for normal use.
Ericrobertson1978 t1_jeggdrx wrote
Yeah. That's the one.
It's like putting your brain in a blender.
TheGreenKillShirt t1_jeh23og wrote
Took Clonazolam. Ran out. Was terrified and told my wife. Went to the ER at 5am just in case I had a seizure. Had a seizure in the waiting room 20 minutes after arriving. Thank god I told her, or who knows if I would have stopped seizing.
boshbosh92 t1_jegf7so wrote
I thought they all got banned? I know etizolam did at least in my state, and the vendor I would buy from is in federal prison right now for misleading customs. I am definitely on a watch list of some sort
RLDSXD t1_jegrcij wrote
Etizolam got banned in a few places because it’s more well-known. The tough part about figuring out what’s banned and what isn’t is that we’re often dealing with multiple country’s lists of substances; even if a substance is legal here, it may have been banned in the country it’s coming from and vice versa.
A lot of the more popular ones got banned either in the NL or the US recently, I believe, but there’s always another obscure one popping up. Seems like a lot more etizolam analogues than straight up benzo analogues lately.
boshbosh92 t1_jegx3i8 wrote
Ahem could you possibly point me in the direction of an analogue or two, for research purposes of course?
coniferous-1 t1_jegj6yp wrote
What is an "RC benzo"?
DamnThatsLaser t1_jegks6k wrote
"RC" in this context means Research Chemical, these are substances that are usually novel and as such not yet well researched and regulated. They are called research chemicals because you're free to do your own "research on them" since there's no law stopping you from doing it. They often can be ordered from specialized vendors or from another country where manufacturing is done, like India or China.
These can either be actual novel substances in a given class or designer prodrugs that were invented to circumvent existing laws, for the latter 1p-LSD is an example, it's technically not LSD so it was legal but it turns into LSD in your body so it's not only mimicking the effect in another way like NBOMe, but it becomes the real thing. Anyhow, the downside with the other RC drugs is that there's usually little to no reliable scientific information about toxicity and other long term effects.
Benzos which this thread is about is a class of depressant drugs. But I guess you knew that already. I don't think they're very popular over here in Germany though.
coniferous-1 t1_jegljvz wrote
informative, thank you.
parks_canada t1_jegl34r wrote
RC stands for research chemical, and sometimes they're called designer drugs. Really it refers to any chemical that isn't well studied and understood, but typically when people talk about RCs they're referring to drugs that aren't federally scheduled, and which fall into a legal grey area in many cases (allowing them to be sold on the open market). A lot of these are analogues of scheduled drugs, for example:
- Clonazolam ("CLAM"), an analogue of clonazepam (Klonopin)
- 1P-LSD, an analogue of LSD
- MDMC, an analogue of MDMA
coniferous-1 t1_jeglinv wrote
Informative, thank you.
PK1312 t1_jegnhlb wrote
one little addition because i think the chemistry is cool- 1P-LSD is also a prodrug of LSD, meaning it turns into actual LSD inside your body, which is neat. It's like psilocybin in mushrooms- psilocybin by itself is not psychoactive, but in the acidic conditions of the stomach it turns into psilocin- the thing that actually makes you trip.
coniferous-1 t1_jegnvsr wrote
Like amphetamine and vyvance.
[deleted] t1_jegngks wrote
[deleted]
Srnkanator t1_jegt819 wrote
That's 950 milligrams, almost ten times a standard dose of Valium.
As someone trying to abstain, I just use 30 mg a day spread every 6-8 hours out when I withdraw.
shockencock t1_jege75h wrote
How much lorazepam did you have?
Prinzka t1_jegef12 wrote
About 50mg
shockencock t1_jegehos wrote
Impossible. You would be dead
Prinzka t1_jegfo73 wrote
Lol
Lorazepam has an ld50 of nearly 2g/kg.
That's the whole reason OP made this post, they were wondering why you can take high doses of benzos without dying even though it's a cns depressant.
shockencock t1_jegfze2 wrote
I guess you are right. Most people that try to kill themselves with it drink alcohol too. I stand corrected. I couldn’t imagine taking 50 mg of it.
Prinzka t1_jeggj2d wrote
> Most people that try to kill themselves with it drink alcohol too.
Yeah and then you need a lot less, that's the danger.
>I couldn’t imagine taking 50 mg of it.
Tbf, I can only imagine it.
About an hour after I took the first 4mg I don't recall anything for the next day or so.
I took the rest of the bottle I had I'm assuming because I forgot that I'd already taken some.
There was never an intent to take the whole bottle, just the first ones made me not form any new memories....
wighty t1_jegvuav wrote
IIRC the pharmacist that did our benzo lecture called it a "ceiling effect", benzos will only cause so much respiratory depression but not enough to stop you breathing. Add alcohol to the mix, though, and you absolutely can overdose yourself and stop breathing.
effrightscorp t1_jegevz4 wrote
50 mg lorazepam won't even kill a rat
shockencock t1_jegf1ja wrote
You have it confused with another benzo. 50 mg of lorazepam will kill you in about an hour
effrightscorp t1_jegfzyj wrote
LD50 is 1850 mg/kg in mice, so it takes around 40 mg to kill an average one. Here's a case study where one guy took 100 mg, one woman took 120 mg and both were out of the hospital within a few days and didn't really need any treatment
You can take stupid big overdoses of benzos and survive because they all have pretty good therapeutic indices. The bigger issue is that, if you don't pass out, you'll probably run out blacked out and can do enough stupid shit to end up in jail etc
shockencock t1_jegfcqz wrote
My brother is a psychiatric nurse in a hospital. He would inject 2 mg of lorazepam into patients then put them into seclusion to sleep it off. The starting dose for lorazepam is like .5 mg
effrightscorp t1_jeggc1l wrote
That says nothing about the lethal dose, which is much higher than 50 mg in humans
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