Submitted by kaisermikeb t3_123fpoo in explainlikeimfive
Was it illegal for big pharma to utilize the stuff? Are laboratory created drug classes genuinely better and the CBD stuff is just like crystals and prayer pushed by stoners? Did the scientists just like... overlook it? Surely some of them were smoking up after work...
Maybe not in the U.S. but believe that research done in other places is still applicable here. This is an unintelligent conversation. For example L.S.D has never been legal here nor have psychedelic mushrooms but there has been abundant research done on how it affects people. Just because something is not legal for recreational consumption does NOT mean there hasn't been research done.
From one link: CBD has a significant therapeutic effect for epilepsy (SMD − 0.5[CI − 0.62, − 0.38] high grade) and Parkinsonism (− 0.41[CI − 0.75, − 0.08] moderate grade).
The other link is about Phase II clinical trials, i.e. ongoing research.
The point stands that there is as of yet insufficient research done to say that CBD is a fit medicine for anxiety/depression. That nature link literally says: "Evidence suggests cannabidiol (CBD) has anxiolytic properties, indicating potential for novel treatment strategies."
Suggests. Potential.
Dude, did you even read your own sources?
"...few clinical trials of CBD-based products have been conducted, and none thus far have examined the impact of these products on cognition."
"Results provide preliminary evidence supporting efficacy and tolerability of a full-spectrum, high-CBD product for anxiety...A definitive assessment of the impact of this novel treatment on clinical symptoms and cognition will be ascertained in the ongoing double-blind, placebo-controlled stage."
This paper was just published a few months ago as well. The rigorous study of CBD is still very young. Due to the War on Drugs, there have been very few well-designed late phase clinical trials for CBD.
There was little research done for many years. The trouble once anything is declared a controlled substance research become very hard due the need to secure the substance at the lab, getting it to the lab and anywhere you need to take the substance. All this is after convincing the government that you have a case that the substance will do what you think it will and that medical use will not cause the substance to be abused. If you jump through all the hoops and complete all the mountains of paperwork, you finally have to source and import the substance. This will require more paperwork and so on in the source country.
Marijuana is a schedule 1 drug according to the DEA. That means it is considered to have no therapeutic use and a high potential for abuse and addiction. That is the most restricted category, even drugs like cocaine and fentanyl are not schedule 1 substances. Drugs in that group are the most restricted for scientists to study so in addition to all the other barriers keeping scientists from studying what they want there are a ton of government hoops to jump through. Marijuana was originally criminalized for culture war reasons and it is still a schedule 1 drug 100+ years later. There are also a bunch of fun laws like if you're a gun owner and you use marijuana, even in a state where it's legal, you're not allowed to own your guns anymore.
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Baktru t1_jduh18n wrote
CBD was a controlled substance, i.e. illegal until 2018 in the USA. There's hardly been any medical research around the medicinal benefits of CBD anyway, so you can't even say that CBD works for depression and/or anxiety. There simply isn't research confirming that. The only confirmed medicinal use of it is for certain types of seizures.