There's exactly one kind of colour space where blending colours makes any sense and it's the ones where colours are a simple linear transformation of the light spectrum. For humans you'll want to use either CIE XYZ or CIE RGB (the end result is equivalent). In these spaces blending colours has the same effect as blending light of the same colour, which is usually what you want.

If you use non-linear spaces you're not blending you're 'tweening' colours at best, doesn't matter if the space is perceptually uniform or not. This can be helpful for graphic design, but it's not physically meaningful and usually has some weird edge-cases.