I'd like to see some doctors turn from a punitive and sometimes deadly approach with Vicodin.

I have chronic nerve damage pain, and I had to pressure my otherwise sympathetic doctor, to remove the acetaminophen from my daily dosage.

If they had not done that, I would surely have died by now of liver and kidney failure, over the past decade.

Kidney/liver issues definitely, but also genetics can affect drug distribution and elimination for many medications (for example, loss or gain of function mutations in drug transporters).