Submitted by cheekychessie t3_10fbg7v in askscience
venom121212 t1_j4wrp6e wrote
Reply to comment by cheekychessie in What specifically keeps viruses from moving from human to animal or vice versa in most cases? by cheekychessie
It's more like covid evolved in its host species to a form where it was able to affect humans.
To oversimplify things:
Picture a virus as a really funky key. Your cells (animal cells) are covered in funky looking locks. These locks are meant to allow good things in while generally keeping bad stuff out, all throughout your body. When a virus mutates, it is finding a way to spread more efficiently and effectively. One of these methods is by changing binding protein shape to fit more locks.
Similar situation with swine flu, avian flu, and many other zoetic viruses. We keep an eye on which animal viruses are getting dangerously close to making the human jump by taking animal cell lines, replacing the receptors (locks from earlier) with human versions, and then seeing if the virus is able to bind and replicate.
cheekychessie OP t1_j4wuipq wrote
So cool. Thanks for explaining it in terms I can understand! You rock
[deleted] t1_j4wv7uq wrote
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