PsychoticGiggle t1_j4jdokz wrote
Reply to comment by DukeSuperior_Truth in How do the new generation of weight loss drugs (Semaglutide, tirzepatide) work and why are they seemingly so effective? by harpoonhambone
It definitely works without lifestyle modification, because it still reduces appetite. But all the research has been done on patients that they also promoted lifestyle modification to. And ultimately if someone stops taking the medication hopefully it has helped with lifestyle changes to reduce the amount of weight regained.
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